Asgard Therapeutics AB, Lund, Sweden

Asgard Therapeutics is a privately held development stage biotech company, pioneering in vivo direct cell reprogramming for cancer immunotherapy. Asgard Therapeutics closed a EUR30million Series A to support the development of the lead program, AT-108 into clinical stage. AT-108 is  a first-in-class, off-the-shelf gene therapy, that directly reprograms tumor cells into antigen-presenting conventional Type 1 Dendritic Cells, a rare subset of immune cells critical for effective anti-tumor immunity. In vivo Proof-of concept for this unique approach was published in Science last year. Asgard Therapeutics is expanding its multidisciplinary team with a Scientific Operations Manager.

Position Overview

We are seeking a highly enthusiastic Scientific Operations Manager who is looking for an opportunity to support a drug development research team, help build an early-stage company and contribute to the development of next-generation cancer immunotherapies. The ideal candidate should have experience from a GLP laboratory in industry setting, leading SOP writing and framework, H&S oversight and project coordination with external collaborators. The successful candidate should have the ability to ensure compliance of safe and efficient laboratory operations by overseeing implementation/update of satisfactory procedures and policies for laboratory safety, training, inventory, equipment maintenance and ELN reporting. The candidate will also support projects with external stakeholders by coordinating project deliveries and revision of legal agreements and contracts. Strong interpersonal, verbal, and written communication skills are required, along with high level of attention to detail, effective time management, and the ability to coordinate complex projects. This position is based at our facilities in Lund, Sweden.

Responsibilities

  • Manage, draft and review Standard operating Procedures and Polices for lab procedures and equipment and support writing SOPs for scientific assays.
  • Health and Safety oversight, drafting and reviewing H&S policies and SOPs and ensuring lab operations are compliant with internal and external safety regulations.
  • Manage Cell and Virus Biobank, overseeing material traceability, stock control and risk mitigations procedures.
  • Main contact for collaborators and CROs for the research pipeline, coordinate project deliveries, reports and sample or material shipments, aligning deliveries and project timelines with company goals.
  • Oversee lab operations including coordination of centralized lab ordering, stock control, equipment purchases and maintenance, managing supplier relations and negotiating annual price agreements.
  • Manage ELN system including training and supporting personal as well as reviewing laboratory notebook and the associated project reports to ensure quality standards, accuracy, and completeness are met.
  • Support drafting and review of legal document such as Statement of Work, Master Service Agreements, documentation related to Grants, among others, articulating communication between R&D and Legal teams.

Profile

Essential

  • MSc in a relevant scientific discipline (e.g., Biomedicine, Cell Biology, Immunology, Cancer Biology)
  • Minimum 2 years of laboratory management experience in academia or industry including writing SOPs.
  • Proven ability to manage projects with a track record of meeting deadlines and objectives.
  • High level of attention to detail
  • Strong interpersonal, verbal, and written communication skills
  • English Proficiency

Desirable

  • PhD in a relevant scientific discipline (e.g., Biomedicine, Cell Biology, Immunology, Cancer Biology)
  • 3-5 years of laboratory management experience in industry including H&S oversight
  • Experience in maintaining supplier relationships and price agreement negotiation
  • Experience in cancer immunotherapy, cell reprogramming or gene therapy
  • Swedish Proficiency

Literature

  • Ascic E, at al. In vivo dendritic cell reprogramming for cancer immunotherapy. Science 386, eadn9083 (2024). DOI:10.1126/science.adn9083
  • Zimmermannova O, et al. Restoring Tumor Immunogenicity with Dendritic Cell Reprogramming. Science Immunology 8, eadd4817 (2023). DOI: 10.1126/sciimmunol.add4817

Application

Please email your CV, cover letter and contact information for two references to careers@asgardthx.com to apply. Asgard will review applications on a rolling basis and only shortlisted candidates will be contacted.

Job type Full time
Salary Commensurate with role and experience.